Macrophage reaction against sub-micron titanium particles
Macrophage reaction against sub-micron titanium particles
复制标题
巨噬细胞对亚微米钛颗粒的反应
DOI：
10.1007/978-4-431-54070-0_84
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
S.
中科院分区：
文献类型：
--
作者：
Taira;M.;Sasaki;M. and Kimura;S.
钛种植体周围有时会出现种植体周围炎，本研究阐明了巨噬细胞积极吞噬并在细胞内细化亚微米钛颗粒（模拟磨损碎屑），同时产生大量的炎性细胞因子。同时用钛颗粒和脂多糖（LPS）刺激，炎性细胞因子的量显着增加。
Around titanium (Ti) implants, peri-implantitis is sometimes found. This study clarified that macrophage actively phagocytized and intra-cellulary refined sub-micron Ti particles (simulated wear debris) while producing abundant inflammatory cytokines. The amounts of inflammatory cytokines were significantly increased by concomitant stimulation with Ti particles and lipopolysaccharide (LPS).