Fluorescent Diarylindoles by Palladium-Catalyzed Direct and Decarboxylative Arylations of Carboxyindoles
Fluorescent Diarylindoles by Palladium-Catalyzed Direct and Decarboxylative Arylations of Carboxyindoles
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DOI：
10.1002/chem.200900098
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发表时间：
2009-01-01
影响因子：
4.3
通讯作者：
Miura, Masahiro
中科院分区：
文献类型：
--
作者：
Miyasaka, Mitsuru;Fukushima, Azusa;Miura, Masahiro
简单明了：1-取代的1H-吲哚-2-羧酸在钯催化体系中与芳基溴化物反应，有效地发生了连续的二芳化反应，伴随着C-氢键的断裂和脱羧基反应，得到了荧光的2，3-二芳基吲哚。这种简便的合成方法提供了一种高效的蓝色发射体，在固态下的量子产率为0.97(见方案)。
Simple and brilliant: 1‐Substituted 1H‐indole‐2‐carboxylic acids efficiently undergo successive diarylation accompanied by CH bond cleavage and decarboxylation upon treatment with aryl bromides in the presence of a palladium catalyst system to afford fluorescent 2,3‐diarylindoles. This facile synthetic method provides a highly efficient blue emitter with a quantum yield of 0.97 in the solid state (see scheme).