Deroofing: An Effective Method for Treating Chronic Diffuse Hidradenitis Suppurativa
Deroofing: An Effective Method for Treating Chronic Diffuse Hidradenitis Suppurativa
复制标题
去顶：治疗慢性弥漫性化脓性汗腺炎的有效方法
作者：
Cen;Kao‐ping Chang;Shu
化脓性汗腺炎，也被称为反转痤疮，是一种具有挑战性的皮肤病。它被认为是一种慢性炎症状态，与滤泡闭塞有关，由角蛋白清除缺陷引起。当这些扩张的毛囊破裂时，积累的角蛋白碎片会引起炎症，这可能会导致额外的窦道或囊肿伴脓液和随后的表皮增生。这种疾病的患者通常报告由复发的脓肿形成和皮下瘘管引起的疼痛。化脓性汗腺炎的患病率在西方从1%到4%不等，在日本从0.033%到0.4%不等。化脓性汗腺炎主要发生在青壮年。吸烟和肥胖被发现与这种疾病有关。Hurley系统通常用于确定化脓性汗腺炎的临床分期。这个系统的第二阶段的特点是鼻窦束和疤痕形成，这些在第一阶段是不存在的，而第三阶段的特点是整个区域都有弥漫性(或几乎弥漫性)病变。
Hidradenitis suppurativa, also known as acne inversa, is a challenging skin disorder. It is identified as a chronic inflammatory condition related to follicular occlusion that results from a keratin-clearance defect. When these dilated follicles rupture, accumulated keratin debris induces inflammation,which can lead to additional sinus tracts or cysts with pus and subsequent epidermal hyperplasia. Patients with this disease typically report pain induced by the recurrent abscess formation and subcutaneous fistulas. The prevalence of hidradenitis suppurativa ranges from 1% to 4% in theWest and 0.033% to 0.4% in Japan. Hidradenitis suppurativa occurs primarily in young adults. Smoking and obesity have been found to be associated with the disorder. The Hurley system has commonly been used for determining the clinical staging of hidradenitis suppurativa. Stage II of this system is characterized by sinus tracts and scarring that are not present at Stage I, and Stage III is characterized by a diffuse (or nearly diffuse) lesion over the entire area.