COVID-19-associated meningoencephalitis complicated with intracranial hemorrhage: a case report

COVID-19-associated meningoencephalitis complicated with intracranial hemorrhage: a case report
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DOI:
10.1007/s00701-020-04402-w
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发表时间:
2020-05-20
影响因子:
2.4
通讯作者:
Garozzo, Debora
Garozzo, Debora
中科院分区:
医学3区
文献类型:
--
作者:
Al-olama, Mohammad;Rashid, Anas;Garozzo, Debora

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2019年12月开始的冠状病毒大流行主要与与呼吸道症状一致的临床表现有关;然而,关于神经系统并发症的报道最近出现在医学文献中。我们描述了一个36岁的冠状病毒阳性患者急诊入院的病例;他的临床表现包括神经系统症状,如嗜睡和轻度精神错乱。影像显示脑膜脑炎合并脑内血肿及硬膜下血肿。后者在变成慢性后通过手术排出,并在液体中发现了冠状病毒的证据。我们的经验证实,神经系统并发症可能是COVID-19的一个可能事件。虽然不常见,但参与COVID-19患者管理的医生应牢记脑膜脑炎的可能发生。早期识别脑受累可能提供更好的预后,防止演变为脑出血事件。
The coronavirus pandemic that started in December 2019 is mainly related to clinical pictures consistent with respiratory symptoms; nevertheless, reports about neurological complications have recently appeared in the medical literature. We describe a case of a 36-year-old coronavirus-positive patient that was admitted on emergency basis; his clinical presentation included neurological symptoms such as drowsiness and mild confusion. Imaging revealed findings consistent with meningoencephalitis complicated by intracerebral hematoma and subdural hematoma. The latter was surgically evacuated after it became chronic and evidence of coronavirus was found in the fluid. Our experience confirms that neurological complications might be a likely event in COVID-19. Although uncommon, the possible occurrence of meningoencephalitis should be kept in mind by physicians involved in the management of COVID-19 patients. Early recognition of brain involvement may provide better prognosis, preventing evolution into intracerebral hemorrhagic events.