Invariant visual representation by single neurons in the human brain
Invariant visual representation by single neurons in the human brain
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DOI：
10.1038/nature03687
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发表时间：
2005-06-23
期刊：
影响因子：
64.8
通讯作者：
Fried, I
中科院分区：
文献类型：
--
作者：
Quiroga, RQ;Reddy, L;Fried, I
即使在截然不同的条件下，识别一个人或一个物体也只需要几分之一秒。人类大脑中的神经元是如何实现这种强大的高层次表示的，目前还不清楚（1-6）。在猴子中，腹侧视觉通路的上层神经元对复杂图像（如面部和物体）做出反应，并对刺激大小、位置和视角等度量属性表现出一定程度的不变性（2，4，7 -12）。我们之前已经表明，人类内侧颞叶（MTL）中的神经元选择性地对面部，动物，物体或场景的图像进行激发（13，14）。在这里，我们报告了一个显着的MTL神经元的子集，选择性激活的显着不同的图片给定的个人，地标或对象，在某些情况下，甚至是字母串与他们的名字。这些结果表明，一个不变的，稀疏和明确的代码，这可能是重要的复杂的视觉感知到长期和更抽象的记忆的转换。
It takes a fraction of a second to recognize a person or an object even when seen under strikingly different conditions. How such a robust, high-level representation is achieved by neurons in the human brain is still unclear(1-6). In monkeys, neurons in the upper stages of the ventral visual pathway respond to complex images such as faces and objects and show some degree of invariance to metric properties such as the stimulus size, position and viewing angle(2,4,7-12). We have previously shown that neurons in the human medial temporal lobe (MTL) fire selectively to images of faces, animals, objects or scenes(13,14). Here we report on a remarkable subset of MTL neurons that are selectively activated by strikingly different pictures of given individuals, landmarks or objects and in some cases even by letter strings with their names. These results suggest an invariant, sparse and explicit code, which might be important in the transformation of complex visual percepts into long-term and more abstract memories.