Reflex vasoconstriction to a cold stimulus for non-invasive evaluation of neurovascular function in man.
Reflex vasoconstriction to a cold stimulus for non-invasive evaluation of neurovascular function in man.
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对冷刺激的反射性血管收缩，用于对人体神经血管功能的无创评估。
DOI：
10.1536/ihj.20.301
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发表时间：
1979
期刊：
影响因子：
--
通讯作者：
Y. Hirasawa
中科院分区：
文献类型：
--
作者：
Y. Aizawa;A. Shibata;M. Tajiri;Y. Hirasawa
采用静脉阻断技术测定了30例健康人肢体血流对冷刺激的反应。通过将一只手浸入冰水中35秒来施加应力，并连续测量对侧上肢的血流量。在间歇性测量中，第15秒应力时的血流量变化最大，并降低了对照值的48+/-8%。一个显着的上升，血浆多巴胺-β-羟化酶被发现在响应相同的压力。这种简单的冷应激试验可用于评价参与反射性血管收缩的反射弧的功能。在12例尿毒症患者中观察到血管收缩显著减少，同时血浆多巴胺-β-羟化酶活性升高较小。
The response of limb blood flow to cold stimulus was determined by venous occlusion technique in 30 healthy subjects. The stress was applied by immersing one hand into ice-floating water for 35 sec, and the blood flow was measured serially in the contralateral upper limb. The change of blood flow at the 15th sec of stress was the largest among the intermittent measurements, and decreased by 48+/-8% of the control value. A significant rise in plasma dopamine-beta-hydroxylase was found in response to the same stress. This simple cold stress test may be used to evaluate the function of the reflex arc involved in reflex vasoconstriction. A significantly diminished vasoconstriction was observed in 12 uremic patients with a concomitantly smaller rise of plasma dopamine-beta-hydroxylase activity in the test.