Intensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications
Intensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications
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DOI：
10.1186/1748-717x-5-17
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发表时间：
2010-02-26
影响因子：
3.6
通讯作者：
Aristu, Javier
中科院分区：
文献类型：
--
作者：
Arbea, Leire;Isaac Ramos, Luis;Aristu, Javier
目的：比较局部进展期直肠癌（LARC）患者在使用经典解剖标志的3DCRT（c3DCRT）、符合PTV的3DCRT（f3DCRT）和调强放疗（IMRT）中的靶区剂量分布、共形性、正常组织回避和照射体体积（IBV）。目标的定义遵循了红十字会第50和62号报告书的建议。OAR（SB和膀胱）限制为D5
Purpose: To compare target dose distribution, comformality, normal tissue avoidance, and irradiated body volume (IBV) in 3DCRT using classic anatomical landmarks (c3DCRT), 3DCRT fitting the PTV (f3DCRT), and intensity-modulated radiation therapy (IMRT) in patients with locally advanced rectal cancer (LARC).Materials and methods: Fifteen patients with LARC underwent c3DCRT, f3DCRT, and IMRT planning. Target definition followed the recommendations of the ICRU reports No. 50 and 62. OAR (SB and bladder) constraints were D5