Electroconvulsive shock prevents dopamine receptor supersensitivity.
Electroconvulsive shock prevents dopamine receptor supersensitivity.
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电休克可防止多巴胺受体超敏反应。
DOI：
10.1016/0014-2999(82)90188-1
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发表时间：
1982
影响因子：
5
通讯作者：
R. Belmaker
中科院分区：
文献类型：
--
作者：
B. Lerer;K. Jabotinsky;J. Bannet;R. Ebstein;R. Belmaker
据报道，电惊厥休克可增加多巴胺受体的敏感性，如行为学测量，但以前没有变化可以测量生化。当慢性氟哌啶醇治疗用于诱导超敏反应作为外源性或病理性受体变化的模型时，发现电休克可在生化和行为上稳定多巴胺受体。
Electroconvulsive shock has been reported to increase dopamine receptor sensitivity as measured behaviorally, but no change could previously be measured biochemically. When chronic haloperidol treatment was used to induce supersensitivity as model of exogenous or pathologic receptor changes, electroconvulsive shock was found to stabilize the dopamine receptor both biochemically and behaviorally.