SARS-CoV-2 in the ocular surface of COVID-19 patients
SARS-CoV-2 in the ocular surface of COVID-19 patients
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DOI：
10.1186/s40662-020-00189-0
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发表时间：
2020-04-26
期刊：
影响因子：
4.2
通讯作者：
Zhang, Ming-Chang
中科院分区：
文献类型：
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作者：
Xie, Hua-Tao;Jiang, Shi-Yun;Zhang, Ming-Chang
由严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的2019年新型冠状病毒病(新冠肺炎)已在全球蔓延，但该病毒的传播途径仍存在争议。我们招募了33名没有任何眼部表现的患者，收集他们的眼表拭子进行病毒检测。从两名患者的双眼样本中检测到RNA强阳性。因此，新冠肺炎患者正常眼表可能存在SARS-CoV-2，提示该病毒可能通过结膜接触传播。
The 2019 novel coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally, while the routes of transmission of this virus are still controversial. We enrolled 33 patients, without any ocular manifestation, with their ocular surface swabs collected for virus detection. RNA was detected strong positive in samples of both eyes from two patients. Therefore, SARS-CoV-2 may exist in the normal ocular surface of COVID-19 patients, suggesting that this virus might be spread through conjunctival contact.