Spatial Epidemiologic Trends and Hotspots of Leishmaniasis, Sri Lanka, 2001-2018
Spatial Epidemiologic Trends and Hotspots of Leishmaniasis, Sri Lanka, 2001-2018
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DOI：
10.3201/eid2601.190971
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发表时间：
2020-01-01
影响因子：
11.8
通讯作者：
Zhou, Guofa
中科院分区：
文献类型：
--
作者：
Karunaweera, Nadira D.;Ginige, Samitha;Zhou, Guofa
利什曼病是一种被忽视的热带疾病，在南亚的发病率正在下降。然而，自2001年以来，斯里兰卡皮肤利什曼病病例有所增加，且缺乏对其流行病学特征的深入研究，阻碍了控制工作。我们分析了 2001 年至 2018 年从斯里兰卡皮肤利什曼病患者收集的数据，以研究时间和地理趋势，并识别和监测疾病热点。我们注意到病例发生率的进展，包括 2018 年的急剧上升，表明疾病流行地区和 2 个持续热点的时间扩张。北部热点随着时间的推移而移动和缩小，但南部热点逐渐扩大并在空间上保持静止。此外，我们还注意到年龄和性别的地区发病率差异。我们提供的证据表明，斯里兰卡利什曼病的发病率在时间上不断增加，在空间上不断扩大，具有独特的地理模式和疾病热点，这表明迫切需要有效的疾病控制干预措施。
Leishmaniasis, a neglected tropical disease, is on the decline in South Asia. However, cases of cutaneous leishmaniasis have risen in Sri Lanka since 2001, and the lack of in-depth research on its epidemiologic characteristics hampers control efforts. We analyzed data collected from patients with cutaneous leishmaniasis in Sri Lanka during 2001-2018 to study temporal and geographic trends and identify and monitor disease hotspots. We noted a progression in case rates, including a sharp rise in 2018, showing temporal expansion of disease-prevalent areas and 2 persistent hotspots. The northern hotspot shifted and shrank over time, but the southern hotspot progressively expanded and remained spatially static. In addition, we noted regional incidence differences for age and sex. We provide evidence of temporally progressive and spatially expanding incidence of leishmaniasis in Sri Lanka with distinct geographic patterns and disease hotspots, signaling an urgent need for effective disease control interventions.