THE HISTONES OF CHICKEN ERYTHROCYTE NUCLEI.
THE HISTONES OF CHICKEN ERYTHROCYTE NUCLEI.
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鸡红细胞核的组蛋白。
DOI：
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发表时间：
1964
期刊：
影响因子：
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通讯作者：
K. Murray
中科院分区：
文献类型：
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作者：
J. M. Neelin;P. Callahan;D. Lamb;K. Murray
用离子交换层析法分离了5个鸡红细胞组蛋白组分，并与小牛胸腺组蛋白组分在氨基酸组成、淀粉凝胶电泳行为、N端氨基酸含量和胰蛋白酶肽指纹图谱等方面进行了比较。一个主要的红细胞组蛋白组分，富含赖氨酸和精氨酸，以及丝氨酸，是这些单一细胞所特有的，并出现取代其他体细胞组织的“富含精氨酸”的组蛋白。相比之下，其他四个红细胞组蛋白组分在种类上与小牛组织中的色谱对应物非常相似，尽管在数量和产量上存在一些差异。这种不寻常的组蛋白的发生可能与这些具有高度分化的细胞核的有限的生物合成能力有关。
Five fractions of chicken erythrocyte histone have been obtained by ion-exchange chromatography, and compared with calf thymus histone fractions in amino acid composition, electrophoretic behavior in starch gel, N-terminal amino acid content, and fingerprint of tryptic peptides. A major erythrocyte histone fraction, rich in both lysine and arginine, as well as serine, was peculiar to these singular cells, and appeared to replace the "arginine-rich" histone of other somatic tissues. In contrast, the other four erythrocyte histone fractions were closely similar in kind to their chromatographic counterparts in calf tissues, despite some differences in number and yield. The occurrence of this unusual histone may be related to the limited biosynthetic capacities of these cells with highly differentiated nuclei.