Genetic overlap between idiopathic pulmonary fibrosis and COVID-19
Genetic overlap between idiopathic pulmonary fibrosis and COVID-19
复制标题
特发性肺纤维化和 COVID-19 之间的基因重叠
DOI：
10.1101/2021.12.08.21267459
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Allen R
中科院分区：
文献类型：
--
作者：
Allen R
2019冠状病毒病（COVID-19）是一种可能导致长期呼吸道症状的传染病，已导致全球超过400万人死亡。特发性肺纤维化（IPF）是一种慢性间质性肺病（ILD），其特征是对肺泡损伤的异常反应，导致肺部进行性瘢痕形成。ILD患者死于COVID-19的风险更高[1]。
Coronavirus disease 2019 (COVID-19) is an infectious disease potentially leading to long lasting respiratory symptoms and has resulted in over 4 million deaths worldwide. Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease (ILD) characterised by an aberrant response to alveolar injury leading to progressive scarring of the lungs. Individuals with ILD are at a higher risk of death from COVID-19 [1].