Accuracy and precision of radioactivity quantification in nuclear medicine images.
Accuracy and precision of radioactivity quantification in nuclear medicine images.
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DOI：
10.1053/j.semnuclmed.2011.11.003
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发表时间：
2012-05
影响因子：
4.9
通讯作者：
Ljungberg M
中科院分区：
文献类型：
--
作者：
Frey EC;Humm JL;Ljungberg M
可靠地量化核医学活动的能力有许多越来越重要的应用。用于靶向治疗计划或用于批准新成像剂的剂量测定需要在几个成像时间点准确估计器官、肿瘤或体素中的活性。另一个重要的应用是使用来自图像的定量度量，例如正电子发射断层扫描（PET）中常用的标准摄取值，以诊断和跟踪肿瘤的治疗。这些措施需要在核医学图像中量化器官或肿瘤活动。然而，有许多物理，病人和技术因素限制了核医学图像的定量可靠性。在仪器方面已经有了大量的改进，包括混合单光子发射计算机断层扫描/计算机断层扫描和PET/计算机断层扫描系统的开发，以及重建方法，包括使用统计迭代重建方法，这大大提高了从平面、单光子发射计算机断层扫描和PET图像获得可靠定量信息的能力。
The ability to reliably quantify activity in nuclear medicine has a number of increasingly important applications. Dosimetry for targeted therapy treatment planning or for approval of new imaging agents requires accurate estimation of the activity in organs, tumors, or voxels at several imaging time points. Another important application is the use of quantitative metrics derived from images, such as the standard uptake value commonly used in positron emission tomography (PET), to diagnose and follow treatment of tumors. These measures require quantification of organ or tumor activities in nuclear medicine images. However, there are a number of physical, patient, and technical factors that limit the quantitative reliability of nuclear medicine images. There have been a large number of improvements in instrumentation, including the development of hybrid single-photon emission computed tomography/computed tomography and PET/computed tomography systems, and reconstruction methods, including the use of statistical iterative reconstruction methods, which have substantially improved the ability to obtain reliable quantitative information from planar, single-photon emission computed tomography, and PET images.
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影响因子：
10.6
作者：
Beekman, FJ;de Jong, HWAM;van Geloven, S
通讯作者：
van Geloven, S
DOI：
10.1007/s00259-002-0796-3
发表时间：
2002-07-01
影响因子：
9.1
作者：
Burger, C;Goerres, G;von Schulthess, GK
通讯作者：
von Schulthess, GK
DOI：
10.1007/s002590100551
发表时间：
2001-07-01
期刊：
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
影响因子：
--
作者：
Dewaraja, YK;Ljungberg, M;Koral, KF
通讯作者：
Koral, KF
影响因子：
1.8
作者：
FLOYD, CE;JASZCZAK, RJ;COLEMAN, RE
通讯作者：
COLEMAN, RE
影响因子：
1.8
作者：
FREY, EC;JU, ZW;TSUI, BMW
通讯作者：
TSUI, BMW