Sub-diagnostic psychiatric comorbidity in alcoholics
Sub-diagnostic psychiatric comorbidity in alcoholics
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DOI：
10.1016/j.drugalcdep.2006.08.009
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发表时间：
2007-03-16
影响因子：
4.2
通讯作者：
Scheiner, Diane L.
中科院分区：
文献类型：
--
作者：
Fein, George;Di Sclafani, Victoria;Scheiner, Diane L.
背景资料：酒精使用障碍中的精神共病已明确确立，但大多数研究忽略了不符合诊断标准的精神症状计数数据。我们检查了48名长期戒酒者（LTAA）与48名年龄/性别相当的轻度/非饮酒对照（NC）在焦虑、情绪和外化病理领域的精神症状计数和心理测量。症状计数和心理评估）在每个领域进行了比较：（1）所有的研究参与者，（2）排除个人的终身精神病诊断的域，和（3）排除个人与当前的精神病诊断在domain.Results：精神症状计数和心理病理学是更大的LTAA比NC。这些措施组之间的差异并没有减少删除个人的一生或当前diagnosis.Conclusions：大部分的LTAA和NC之间的差异在精神疾病进行亚诊断精神病理学。与仅使用符合诊断标准的精神病学提供的有限视图相比，使用精神病学和心理异常的连续测量可以更准确地了解精神疾病与酒精中毒共存的情况。(c)2006爱思唯尔爱尔兰有限公司保留所有权利。
Background: Psychiatric comorbidity in alcohol use disorders is clearly established, however most studies ignore data on psychiatric symptom counts that do not meet criteria for a diagnosis. We examined psychiatric symptom counts and psychological measures in the domains of anxiety, mood and externalizing pathology in 48 long-term abstinent alcoholics (LTAA) compared to 48 age/gender comparable light/non-drinking controls (NC).Methods: Continuous measures of pathology (i.e., symptoms counts and psychological assessments) in each domain were compared between groups for: (1) all study participants, (2) excluding individuals with a lifetime psychiatric diagnosis in the domain, and (3) excluding individuals with a current psychiatric diagnosis in the domain.Results: Psychiatric symptom counts and psychological pathology were greater in LTAA than NC. The differences between groups on these measures were not reduced by removal of individuals with lifetime or current diagnoses.Conclusions: The bulk of the difference between LTAA and NC in psychiatric illness was carried by sub-diagnostic psychopathology. In comparison to the limited view provided by using only symptomatology that meets criteria for a diagnosis, the use of continuous measures of psychiatric symptomatology and psychological abnormality yields a much more accurate picture of psychiatric illness co-occurring with alcoholism. (c) 2006 Elsevier Ireland Ltd. All rights reserved.