Structures and absolute stereochemistry of guaiane sesquiterpenoids from the gorgonian Menella woodin
Structures and absolute stereochemistry of guaiane sesquiterpenoids from the gorgonian Menella woodin
复制标题
DOI：
10.1016/j.tetlet.2015.10.102
复制
发表时间：
2015-12-16
影响因子：
1.8
通讯作者：
Stonik, Valentin A.
中科院分区：
文献类型：
--
作者：
Chau Ngoc Diep;Lyakhova, Ekaterina G.;Stonik, Valentin A.
从柳珊瑚Menello woodin中分离出愈创木烷型倍半萜类化合物（1，2），并通过广泛的光谱分析阐明了它们的结构。基于Mosher法的应用，以及环的稳定构象计算，同时将实验电子圆二色谱、核磁共振光谱和比旋光度与量子化学方法理论计算值进行比较，采用一种复杂的方法确定了这些天然产物中不对称中心的构型。（C）2015爱思唯尔有限公司。保留所有权利。
Guaiane sesquiterpenoids (1, 2) were isolated from the gorgonian Menello woodin and their structures elucidated by extensive spectroscopic analysis. A complex approach was used to determine the configurations of the asymmetric centres in these natural products, based on the application of Mosher's method, and the calculation of stable conformations of the rings along with a comparison of experimental ECD, NMR spectra, and specific optical rotations with those theoretically calculated by quantum-chemical methods. (C) 2015 Elsevier Ltd. All rights reserved.