Beneficial Effects of Polyphenol-Rich Chokeberry Juice Consumption on Blood Pressure Level and Lipid Status in Hypertensive Subjects
Beneficial Effects of Polyphenol-Rich Chokeberry Juice Consumption on Blood Pressure Level and Lipid Status in Hypertensive Subjects
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DOI：
10.1089/jmf.2014.0171
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发表时间：
2015-11-01
影响因子：
2.4
通讯作者：
Spasic, Slavica
中科院分区：
文献类型：
--
作者：
Kardum, Nevena;Milovanovic, Branislav;Spasic, Slavica
流行病学研究表明，摄入富含抗氧化剂的食物与降低心血管疾病发病率之间存在正相关关系。多酚被认为是最丰富和最重要的膳食抗氧化剂。本研究的目的是评估食用富含多酚的蔓越莓汁对24小时动态监测血压（BP）水平的影响，这些受试者没有经过药物治疗的正常血压高或1级高血压。23名年龄在33-67岁的受试者（12名男性和11名女性）被招募，并被要求连续4周每天饮用200毫升果汁。根据交感或副交感神经活动的普遍程度，参与者被分为两组。生化参数测量和心率变异性分析也被应用。干预期结束时，平均24小时和清醒状态下的收缩压和舒张压均显著降低(P
Epidemiological studies have shown a positive association between intake of foods rich in antioxidants and lower incidence of cardiovascular disease development. Polyphenols are considered the most abundant and important dietary antioxidants. The aim of this study was to evaluate effects of polyphenol-rich chokeberry juice consumption on 24-h ambulatory monitored blood pressure (BP) level in subjects with no pharmacologically treated high normal BP or grade I hypertension. Twenty-three subjects (12 men and 11 women) aged 33-67 were enrolled and instructed to consume 200mL of juice daily for 4 weeks. Participants were divided in two groups, based on prevalence of sympathetic or parasympathetic activity. Measurements of biochemical parameters and heart rate variability analysis were also applied. At the end of the intervention period, average 24-h and awake systolic and diastolic BP were significantly decreased (P