Acquired immune deficiency syndrome (AIDS). A review.
Acquired immune deficiency syndrome (AIDS). A review.
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获得性免疫缺陷综合症（艾滋病）。
DOI：
10.1001/archinte.143.12.2307
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发表时间：
1983
影响因子：
--
通讯作者：
J. Vieira
中科院分区：
文献类型：
--
作者：
S. Landesman;J. Vieira
获得性免疫缺陷综合症（艾滋病）是一种新发现的病因不明的疾病，其特征是细胞介导的免疫功能系统失调，表现为机会性感染、先前健康的人中出现不寻常的肿瘤（特别是卡波西肉瘤）。男性同性恋者、吸毒者、海地移民和血友病患者构成艾滋病高危人群。该疾病可能是由一种尚未确定的病原体引起的，该病原体通过性接触、血液或血液制品在人与人之间传播。现有的治疗无法逆转潜在的免疫缺陷。两年死亡率超过70%。本文回顾了我们对艾滋病的了解现状。讨论了该疾病的流行病学、诊断、治疗、免疫学和病因学的选定方面。
Acquired immune deficiency syndrome (AIDS) is a newly recognized disease of unknown etiology, characterized by deregulation of the cell-mediated immune function system and manifested by opportunistic infections, unusual neoplasms (particularly Kaposi's sarcoma) in previously healthy persons. Male homosexuals, drug addicts, Haitian immigrants, and hemophiliacs constitute the group at high risk of having AIDS. The disease is probably caused by an as yet unidentified agent that is transmitted from person to person via sexual contact, blood, or blood products. Available therapy cannot reverse the underlying immune defect. Mortality at two years exceeds 70%. This article reviews the current state of our knowledge about AIDS. Selected aspects of the epidemiology, diagnosis, treatment, immunology, and etiology of the disease are discussed.