Mechanical influences on bone development in children
Mechanical influences on bone development in children
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DOI：
10.1530/eje-08-0312
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发表时间：
2008-12-01
影响因子：
5.8
通讯作者：
Fricke, O.
中科院分区：
文献类型：
--
作者：
Schoenau, E.;Fricke, O.
本文综述了评价骨骼肌功能和适应性的方法学概念。现在人们认为骨骼的关键特性是强度而不是重量.并且骨强度的控制主要通过施加在骨上的机械载荷的作用来实现。肌肉收缩对骨骼施加最大的生理负荷，因此骨骼的稳定性必须适应肌肉力量（功能性肌肉-骨骼单位：）。这些建议和建议提出了一个新的概念：骨量和强度不应该与年龄有关。现在有越来越多的证据表明，骨量和力量应该与肌肉功能有关。由此分析，不存在“峰值骨量”这样的实体。目前正在进行许多研究，以评估这些新方法是否增加了个体骨折预测的敏感性和特异性。此外。许多骨研究者的焦点正从骨质量转移到骨几何形状或骨强度以及它们与驱动肌肉系统的关系。
This review focuses on methodological concepts in the evaluation Of skeletal muscle function and on adaptation. It is now thought that the critical property of bone is strength rather than him weight. and that control of bone strength is mainly exercised through the effect of the mechanical loads brought to bear on bone. Muscle contraction places the greatest physiological load on bone, and so the stability of bone must be adapted to muscle strength (the functional muscle-bone unit:). The describe suggestions and recommendations outline a new concept: bone mass and strength should not be related to age. There is now more and more evidence that bone mass and strength should be related to muscle function. Thus analyzed, there is no such entity as 'peak bone mass'. Many studies are presently under way to evaluate whether these novel approaches increase the sensitivity and specificity of fracture prediction in an individual. Furthermore. the focus of many bone researchers is shifting away from bone mass to bone geometry or bone strength and their relationship with the driving muscle system.