Body mass index and risk of pneumonia: a systematic review and meta-analysis
Body mass index and risk of pneumonia: a systematic review and meta-analysis
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DOI：
10.1111/obr.12055
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发表时间：
2013-10-01
期刊：
影响因子：
8.9
通讯作者：
Chu, C.
中科院分区：
文献类型：
--
作者：
Phung, D. T.;Wang, Z.;Chu, C.
我们的荟萃分析的目的是检查模式和性别对体重指数（BMI）-肺炎关系的影响。使用肺炎、BMI和流行病学研究关键词从PubMed、Web of Science、科克伦图书馆数据库中检索已发表的研究。随机效应分析用于估计个体研究的合并效应量。采用科克伦Q检验和异质性指数（I-2）评价异质性，采用Egger检验评价发表偏倚。采用随机效应荟萃回归分析方法，探讨了模式和性别对BMI与肺炎关系的影响。最初共识别出1，531项研究，最终纳入25项研究。合并相对危险度（RR）和荟萃回归模型显示BMI与社区获得性肺炎风险之间存在J形关系（体重不足，RR 1.8，95%置信区间[CI]，1.4-2.2，P
The aims of our meta-analysis were to examine the pattern and gender's influence on body mass index (BMI) - pneumonia relationship. Published studies were searched from PubMed, Web of Science, Cochrane Library databases using keywords of pneumonia, BMI and epidemiologic studies. Random-effects analysis was applied to estimate pooled effect sizes from individual studies. The Cochrane Q-test and index of heterogeneity (I-2) were used to evaluate heterogeneity, and Egger's test was used to evaluate publication bias. Random-effects meta-regression was applied to examine the pattern and gender's influence on BMI-pneumonia relationship. A total of 1,531 studies were initially identified, and 25 studies finally were included. The pooled relative risk (RR) and meta-regression model revealed a J-shaped relationship between BMI and risk of community-acquired pneumonia (underweight, RR 1.8, 95% confidence interval [CI], 1.4-2.2, P