The effect of epidural blockade on gastric intramucosal pH in the peri‐operative period
The effect of epidural blockade on gastric intramucosal pH in the peri‐operative period
复制标题
硬膜外阻滞对围手术期胃粘膜内pH值的影响
作者：
N. Sutcliffe;S. Mostafa;J. Gannon;S. Harper
接受大手术的患者有发生肠道缺血和多器官衰竭的风险。胃血压计提供了一种相对无创的评估肠道血流充分性的方法。在术后期间反复出现内脏缺血发作的患者，胃粘膜内pH值低证明了这一点，他们的死亡率高于那些没有出现这种情况的患者。这项随机对照研究评估了布比卡因硬膜外阻滞对大手术患者胃粘膜内pH值测量的影响。接受硬膜外阻滞的患者术后发生胃粘膜内pH值的比例明显低于对照组(3/15比13/16，p<；0.001)。讨论了这些结果的意义。
Patients undergoing major surgery are at risk of developing gut ischaemia and multiple organ failure. The gastric tonometer provides a relatively non‐invasive method of assessing the adequacy of gut blood flow. Patients who develop repeated episodes of splanchnic ischaemia in the postoperative period, as evidenced by a low gastric intramucosal pH, have a higher mortality than those who do not. This randomised, controlled study was conducted to assess the effect of epidural blockade with bupivacaine on gastric intramucosal pH measurements in patients undergoing major surgery. A significantly lower proportion of patients with epidural blockade developed gastric intramucosal pH values < 7.32 postoperatively compared to controls (3/15 versus 13/16, p < 0.001). The significance of these results is discussed.
影响因子：
8.8
作者：
Crea F;Sun L;Pikor L;Frumento P;Lam WL;Helgason CD
通讯作者：
Helgason CD