Biocuration: Distilling data into knowledge
Biocuration: Distilling data into knowledge
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DOI：
10.1371/journal.pbio.2002846
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发表时间：
2018-04-01
期刊：
影响因子：
9.8
通讯作者：
Wood, Valerie
中科院分区：
文献类型：
--
作者：
Ammari, Mais;Aryamontri, Andrew Chatr;Wood, Valerie
数据，包括通过处理和分析产生的信息，是一种具有可衡量价值的资产。生物研究资金产生的资产是产生的数据，从这些数据中得出的信息，以及最终这些导致的发现和知识。从1665年亨利·奥尔登堡发表第一本科学期刊(《皇家学会学报》)到1879年美国国家医学图书馆的建立到现在，人们一直在努力改进研究人员记录和发现已知知识的方式。研究人员的实验工作建立在多年和(加在一起)价值数十亿美元的早期工作的基础上。如今，由于仪器和技术的进步，加上生产成本的降低，研究人员正在以越来越快的速度生成数据。遗憾的是，研究人员管理和传播其成果的能力没有跟上步伐，因此他们的工作不能发挥最大的影响。最近取得了进展，但需要更多地认识到生物数据资源，包括生物定位，在维护和连接这一日益增长的数据和信息洪流中发挥的重要作用。本文的目的是描述数据作为一种资产的性质，生物计算器在增加其价值中所起的作用，以及一致、实用的方法来衡量有效性，以指导规划和调整生物研究信息资源开发和管理中的成本。
Data, including information generated from them by processing and analysis, are an asset with measurable value. The assets that biological research funding produces are the data generated, the information derived from these data, and, ultimately, the discoveries and knowledge these lead to. From the time when Henry Oldenburg published the first scientific journal in 1665 (Proceedings of the Royal Society) to the founding of the United States National Library of Medicine in 1879 to the present, there has been a sustained drive to improve how researchers can record and discover what is known. Researchers' experimental work builds upon years and (collectively) billions of dollars' worth of earlier work. Today, researchers are generating data at ever-faster rates because of advances in instrumentation and technology, coupled with decreases in production costs. Unfortunately, the ability of researchers to manage and disseminate their results has not kept pace, so their work cannot achieve its maximal impact. Strides have recently been made, but more awareness is needed of the essential role that biological data resources, including biocuration, play in maintaining and linking this ever-growing flood of data and information. The aim of this paper is to describe the nature of data as an asset, the role biocurators play in increasing its value, and consistent, practical means to measure effectiveness that can guide planning and justify costs in biological research information resources' development and management.