RE-UTILIZATION OF LYMPHOCYTE REMNANTS BY RETICULAR CELLS

RE-UTILIZATION OF LYMPHOCYTE REMNANTS BY RETICULAR CELLS
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DOI:
10.1038/1831059a0
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发表时间:
1959-01-01
期刊:
影响因子:
64.8
通讯作者:
HILL, M
HILL, M
中科院分区:
综合性期刊1区
文献类型:
--
作者:
HILL, M

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19571在伦敦的一次会议上讨论了淋巴细胞的行为和功能。由于放射性标记实验的结果2,淋巴细胞核酸或核蛋白的大片段在形成新淋巴细胞的过程中不断重复利用的假说被普遍接受。Trowell3提出了这一观点的形态支持,他证明了在体外吞噬死亡淋巴细胞的过程中,网状细胞被分化为大淋巴细胞。我们已经能够通过在体内淋巴细胞高度溶解期间所做的类似观察来补充他的发现。
THE behaviour and function of lymphocytes were discussed at a meeting in London in 19571. As a consequence of the results of experiments with radioactive labels2, the hypothesis of continuous re-utilization of large fragments of lymphocyte nucleic acids or nucleoproteins during the formation of new lymphocytes was generally accepted. Morphological support for this view has been put forward by Trowell3, who has demonstrated that the reticular cells are differentiated into large lymphocytes in the course of phagocytosis of dead lymphocytesin vitro. We have been able to supplement his findings by similar observations made during the time of heightened lymphocyte dissolutionin vivo.