Comparison of surgical outcomes between sulcus and anterior chamber implanted glaucoma drainage devices.
Comparison of surgical outcomes between sulcus and anterior chamber implanted glaucoma drainage devices.
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DOI：
10.4103/1319-4534.301298
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发表时间：
2020-01
期刊：
影响因子：
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通讯作者：
Ahmad S
中科院分区：
文献类型：
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作者：
Alobaida IA;Malik R;Ahmad S
这项回顾性病例对照横断面研究比较了青光眼引流装置（GDD）与传统前房（AC）沟放置的结局，以检验沟放置导致并发症较少同时保持相似疗效的假设。本研究纳入了2014年1月至2017年12月接受手术的45例沟组患者和60例前房（AC）组患者。收集术前人口统计学资料、手术细节、术后眼内压和并发症。比较两组患者的眼压、用药次数及并发症。P值<5%被认为是统计学显著的。与AC组相比，沟组的总体并发症显著较低，两组之间的IOP降低程度相当。前房沟积血发生率AC组为17例，对照组为3例，两组比较差异有统计学意义（P < 0.05）。与AC组[13眼; 21.7%]相比，沟组[2眼; 4.4%]的严重或晚期并发症（植入物暴露、角膜失代偿、眼内炎、视力不良、脉络膜出血和角膜水肿）显著降低（P < 0.05）。在随访期间，沟组需要较少的药物。与AC植入相比，沟植入GDD导致术后前房积血和严重并发症较少。我们的研究结果与文献一致，即睫状沟植入术对于控制各种类型青光眼的IOP是安全有效的。血管沟与AC植入的内皮细胞损失的长期影响需要进一步评估。
This retrospective case-control cross-sectional study compared the outcomes of sulcus placement of glaucoma drainage devices (GDD) versus traditional anterior chamber (AC) to test the hypothesis that sulcus placement results in fewer complications whilst maintaining similar efficacy. This study included 45 patients in the sulcus group and 60 patients in the anterior chamber (AC) group who had undergone surgery from January 2014 to December 2017. Data were collected on pre-operative demographics, operative details and post-operative intraocular pressure and complications. The IOP, number of medications and complications between the two groups was compared. A P value of <5% was considered statistically significant. The sulcus group had significantly lower overall complications compared to the AC group with a comparable IOP decrease between groups. There were significantly lower rates of hyphaema in the sulcus (3 cases) compared to AC group (17 cases) (P < 0.05). Severe or late complications (implant exposure, corneal decompensation, endophthalmitis, poor vision, choroidal hemorrhage and cornea edema) were significantly lower in the sulcus group [2 eyes; 4.4%] compared to the AC group [13 eyes; 21.7%] (P < 0.05). The sulcus group required fewer medications during the follow-up period. Sulcus implantation of GDD resulted in less postoperative hyphaema and severe complications compared to AC implantation. Our findings concur with the literature that sulcus implantation is safe and effective for controlling IOP for various types of glaucoma. The long-term effects of endothelial cell loss for sulcus versus AC implantation require further evaluation.