Perinatal Outcomes Associated With Management of Stage 1 Hypertension.
Perinatal Outcomes Associated With Management of Stage 1 Hypertension.
复制标题
与 1 期高血压管理相关的围产期结局。
DOI：
10.1097/aog.0000000000005410
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发表时间：
2023
影响因子：
7.2
通讯作者：
Casey,BrianM
中科院分区：
文献类型：
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作者：
Bailey,ErinJ;Tita,AlanTN;Leach,Justin;Boggess,Kim;Dugoff,Lorraine;Sibai,Baha;Lawrence,Kirsten;Hughes,BrennaL;Bell,Joseph;Aagaard,Kjersti;Edwards,RodneyK;Gibson,Kelly;Haas,DavidM;Plante,Lauren;Metz,TorriD;Casey,BrianM
目的：探讨孕妇血压低于130/80 mm Hg和130-139/80-89 mm Hg与妊娠结局的关系。方法：采用开放式、多中心、随机对照试验，对CHAP进行二次分析。将平均血压低于140/90 mm Hg的受试者分为130/80 mm Hg以下，而130-139/80-89 mm Hg为130-139/80-89 mm Hg。主要的综合结果是先兆子痫伴有严重的特征，表明在妊娠35周之前早产，胎盘早剥，或胎儿或新生儿死亡。对于胎龄(SGA)来说，次要结局很小。
OBJECTIVE:To evaluate the association between maternal blood pressure (BP) below 130/80 mm Hg compared with 130–139/80–89 mm Hg and pregnancy outcomes.METHODS:We conducted a planned secondary analysis of CHAP (Chronic Hypertension and Pregnancy), an open label, multicenter, randomized controlled trial. Participants with mean BP below 140/90 mm Hg were grouped as below 130/80 mm Hg compared with 130–139/80–89 mm Hg by averaging postrandomization clinic BP throughout pregnancy. The primary composite outcome was preeclampsia with severe features, indicated preterm birth before 35 weeks of gestation, placental abruption, or fetal or neonatal death. The secondary outcome was small for gestational age (SGA).RESULTS: