An IRON-clad Connection between Aging Organelles.
An IRON-clad Connection between Aging Organelles.
复制标题
衰老细胞器之间的铁一般连接。
DOI：
10.1016/j.cell.2019.12.037
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发表时间：
2020
期刊：
影响因子：
64.5
通讯作者：
Shen,Hongying
中科院分区：
文献类型：
--
作者：
Shen,Hongying
溶酶体（液泡）和线粒体在衰老过程中通过一种尚不清楚的机制相互依赖地衰退。在本期《细胞》中，休斯等人。 (2020)表明，衰老酵母中液泡介导的半胱氨酸区室化缺陷导致铁限制和线粒体功能障碍。
Lysosome (vacuole) and mitochondria decline interdependently during aging through an unclear mechanism. In this issue ofCell, Hughes et al. (2020) show that defective vacuole-mediated cysteine compartmentalization in aging yeast leads to iron limitation and mitochondrial dysfunction.