In vivo oxygen consumption and hemoglobin levels in human thyroarytenoid muscle.

In vivo oxygen consumption and hemoglobin levels in human thyroarytenoid muscle.
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人甲状杓肌的体内耗氧量和血红蛋白水平。

DOI：
10.1002/lary.22225
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发表时间：
2011
期刊：
The Laryngoscope
影响因子：
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通讯作者：
Sciote,JamesJ
Sciote,JamesJ
中科院分区：
--
文献类型：
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作者：
Tellis,CariM;Rosen,ClarkA;Carroll,ThomasL;Fierro,Michael;Sciote,JamesJ

文献摘要

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目的/假设可见光光谱（VLS）是美国食品药品监督管理局批准的TSTAT设备背后的技术，该设备用于通过测量反射的可见光来监测组织氧（StO 2）和相对总血红蛋白（rtHb）水平。这项新的初步研究的目的是确定VLS是否是一种可靠和有效的方法来测量StO 2和rtHb水平的人甲杓/外侧环杓（TA-LCA）肌肉复合体，从而提供有关声带肌肉生理学的信息。研究设计Pre-test/post-test with multiple baselines and two conditions.MethodsVLS measurements were taken at baseline，during exercise，使用非接触式通道端口内窥镜和结果平均基线StO 2为69%，（标准差[SD] = 3.6%），内镜探头为71.5%（SD = 2.8%）。发声期间，LEMG引导探头的StO 2下降至59%（SD = 7%;P= 0.04）。通过LEMG探针测量的平均rtHb在发声期间从基线的144 μM（SD = 165 μM）上升到214 μM（SD = 166 μM，P= 0.34），并且在恢复后回到149 μM（SD = 139 μM，P= 0.85）。在基线和恢复后使用endo-probe测量的平均rtHb为104 μM（SD = 30 μM，P= .76）。结论VLS可用于测量人TA-LCA肌肉复合体运动前后StO 2和rtHb水平的变化。喉镜，121：2429 - 2434，2011
Objectives/HypothesisVisible light spectroscopy (VLS) is the technology behind the Food and Drug Administration–approved TSTAT device that is used to monitor tissue oxygen (StO2) and relative total hemoglobin (rtHb) levels by measuring reflected visible light. The purpose of this novel, pilot study was to determine if VLS is a reliable and valid method of measuring StO2and rtHb levels in the human thyroarytenoid/lateral cricoarytenoid (TA‐LCA) muscle complex, thus providing information about vocal fold muscle physiology.Study DesignPre‐test/post‐test with mulitple baselines and two conditions.MethodsVLS measurements were taken at baseline, during exercise, and following recovery on six subjects using both noncontact channel‐port endoscope (endo‐probe) and laryngeal electromyography (LEMG) needle‐guided techniques.ResultsThe average baseline StO2was 69% (standard deviation [SD] = 3.6%) for the LEMG‐guided probe and was 71.5% (SD = 2.8%) for the endo‐probe. During phonation, the StO2for the LEMG‐guided probe dropped to 59% (SD = 7%;P= .04). Mean rtHb measured by the LEMG probe rose from a baseline of 144 μM (SD = 165 μM) to 214 μM (SD = 166 μM,P= .34) during phonation and back to 149 μM (SD = 139 μM,P= .85) after recovery. Mean rtHb as measured using the endo‐probe at baseline and after recovery was 104 μM (SD = 30 μM,P= .76).ConclusionsVLS can be used to measure changes in StO2and rtHb levels pre‐ and postexercise in the human TA‐LCA muscle complex. Laryngoscope, 121:2429‐2434, 2011