ALTERED LYMPHOCYTE POPULATIONS IN TUMOR INVADED NODES OF BREAST-CANCER PATIENTS
ALTERED LYMPHOCYTE POPULATIONS IN TUMOR INVADED NODES OF BREAST-CANCER PATIENTS
复制标题
DOI:
10.1016/0165-2478(93)90187-7
复制
发表时间:
1993-03-01
影响因子:
4.4
通讯作者:
CAMPBELL, AM
中科院分区:
文献类型:
--
作者:
ALAM, SM;CLARK, JS;CAMPBELL, AM
Lymphocytes from matched pairs of tumour-invaded and tumour-free lymph nodes from 22 stage II breast cancer patients have been analysed for expression of phenotypic and activation markers by flow cytometry. Although the relative proportions of T and B lymphocytes were similar in the two nodes, significant differences in the distribution of T cell subsets were observed between nodes that were invaded and those that were not. The CD4/CD8 ratio was markedly depressed in tumour invaded nodes (P