Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients: A physiologic study

Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients: A physiologic study
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DOI:
10.1016/j.jcrc.2019.06.020
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发表时间:
2019-10-01
影响因子:
3.7
通讯作者:
Grasselli, Giacomo
Grasselli, Giacomo
中科院分区:
医学3区
文献类型:
--
作者:
Mauri, Tommaso;Carlesso, Eleonora;Grasselli, Giacomo

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ROX(呼吸频率-氧合)指数是鼻高流量 (NHF) 失败的早期预测指标,数值越低表明插管风险越高。我们在 57 名接受 NHF 治疗的低氧血症患者中测量了设定流速为 30 和 60 l/min 时的 ROX 指数。与 ROX 指数值不变或降低的患者 (n = 17) 相比,在较高流量时 ROX 指数值增加的患者 (n = 40) 表现出更差的基线氧合、更高的呼吸频率和更低的 ROX 指数。流量之间的 ROX 指数变化与呼气末肺容量的变化相关。 NHF 期间设置的流速可能会影响 ROX 指数值。 (C) 2019 Elsevier Inc. 保留所有权利。
The ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at higher flow (n = 40) showed worse baseline oxygenation, higher respiratory rate and lower ROX index in comparison to patients with unchanged or decreased ROX index values (n= 17). The ROX index variation between flowswas correlated with the change in end expiratory lung volume. Set flow rate during NHF might impact the ROX index value. (C) 2019 Elsevier Inc. All rights reserved.