Mycobacteraemia among HIV-1-infected patients in Sao Paulo, Brazil: 1995 to 1998
Mycobacteraemia among HIV-1-infected patients in Sao Paulo, Brazil: 1995 to 1998
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DOI：
10.1017/s0950268803001535
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发表时间：
2004-01-01
影响因子：
4.2
通讯作者：
Palhares, MCA
中科院分区：
文献类型：
--
作者：
Hadad, DJ;Palaci, M;Palhares, MCA
From July 1995 to August 1998, mycobacterial blood Cultures were obtained from 1032 HIV-infected patients seen at the Centro de Referncia e Treinamento de AIDS (CRTA), Hospital Sao Paulo (HSP), and Centro de Referncia de AIDS de Santos (CRAS). Overall, 179 episodes of mycobacteraemia were detected: 111 (62.0%) at CRTA, 50 (27.9%) at LISP, and 18 (10.1%) at CRAS. The frequency of positive Cultures declined sharply from 22.6%, in 1995 to 6.9% in 1998, consistent with the decrease in opportunistic infections following the publicly funded distribution of highly active anti retroviral therapy. In 1995, mycobacteraemia was more frequently due to Mycobacterium avium complex (59.2%) than Mycobacterium tuberculosis (28.6%), whereas in 1998 the relative frequencies were reversed (28.6 vs. 64.3% respectively), probably justified by the increased virulence of M. tuberculosis and the greater risk of invasive infection in less-immunocompromised patients, including patients unaware they are infected with HIV.
