Six weeks of intensive treadmill training improves gait and quality of life in patients with Parkinson's disease: A pilot study
Six weeks of intensive treadmill training improves gait and quality of life in patients with Parkinson's disease: A pilot study
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DOI：
10.1016/j.apmr.2007.05.015
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发表时间：
2007-09-01
影响因子：
4.3
通讯作者：
Hausdorff, Jeffrey M.
中科院分区：
文献类型：
--
作者：
Herman, Talia;Giladi, Nir;Hausdorff, Jeffrey M.
目的：评估6周强化踏车训练对帕金森病（PD）患者步态节律、功能活动性和生活质量（QOL）的影响。设计：一项开放标签、前后试验性研究。设置：门诊运动障碍门诊。参与者：9名能够独立行走且无痴呆的PD患者。平均年龄为70 ± 6.8岁。患者有轻度至中度PD（Hoehn和Yahr分期范围，1.5-3）。干预措施：患者在每次训练期间在跑步机上行走30分钟，每周4次训练，持续6周。每周一次，重新评估通常的地上步行速度，并相应地调整跑步机速度。主要结果测量：39项帕金森病问卷（PDQ-39），统一帕金森病评定量表（PDRS）的运动部分，步态速度，步幅时间变异性，摆动时间变异性和短期身体性能电池（SPPB）。跑步机干预前后采取的措施的比较表明总体改善。PDQ-39测量的生活质量从32降低（改善）到22（P
Objective: To evaluate the effects of 6 weeks of intensive treadmill training on gait rhythmicity, functional mobility, and quality of life (QOL) in patients with Parkinson's disease (PD).Design: An open-label, before-after pilot study.Setting: Outpatient movement disorders clinic.Participants: Nine patients with PD who were able to ambulate independently and were not demented. Mean age was 70 +/- 6.8 years. Patients had mild to moderate PD (Hoehn and Yahr stage range, 1.5-3).Interventions: Patients walked on a treadmill for 30 minutes during each training session, 4 training sessions a week, for 6 weeks. Once a week, usual overground walking speed was re-evaluated and the treadmill speed was adjusted accordingly.Main Outcome Measures: The 39-item Parkinson's Disease Questionnaire (PDQ-39), motor part of the Unified Parkinson's Disease Rating Scale (UPDRS), gait speed, stride time variability, swing time variability, and the Short Physical Performance Battery (SPPB).Results: A comparison of the measures taken before and after the treadmill intervention indicates general improvement. QOL, as measured by the PDQ-39, was reduced (improved) from 32 to 22 (P