Cardiac metastasis and tumor embolism in a patient with adenocarcinoma of the colon presenting with paraneoplastic polymyositis.

Cardiac metastasis and tumor embolism in a patient with adenocarcinoma of the colon presenting with paraneoplastic polymyositis.
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伴有副肿瘤性多发性肌炎的结肠腺癌患者的心脏转移和肿瘤栓塞。

DOI:
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发表时间:
2013
期刊:
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
影响因子:
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通讯作者:
D. Fodor
D. Fodor
中科院分区:
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文献类型:
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作者:
E. Mihali;M. Mureşan;M. Rusu;D. Fodor

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结直肠癌通常表现为排便习惯的改变。不太常见的是,表现的症状可能是副肿瘤综合征的一部分。转移可以通过淋巴或血行扩散发生,最常见的是肺和肝。我们报告一位56岁男性,因结肠低分化腺癌而罹患副肿瘤性多发性肌炎。进展不利,入院后第19天因肺血栓栓塞和随后的肺水肿死亡。尸检显示心脏、肝脏、肾脏、肾上腺和肺的淋巴和静脉栓塞的微转移。该病例强调了结肠腺癌表现的多样性。
Colorectal cancer usually presents with alterations in the bowel habit. Less commonly, the presenting symptoms may be part of a paraneoplastic syndrome. Metastasis can occur by lymphatic or hematogenous spread, most frequently to the lungs and liver. We present the case of a 56-year-old man admitted with paraneoplastic polymyositis due to a poorly differentiated colon adenocarcinoma. The evolution was unfavorable with death on the 19th day following admission due to pulmonary thromboembolism and subsequent pulmonary edema. Autopsy showed micrometastases with lymphatic and venous emboli to the heart, liver, kidney, adrenal gland and lung. The case highlights the diversity of manifestation that can occur in a colon adenocarcinoma.