Successful bone marrow transplantation in a patient with Schimke immuno-osseous dysplasia
Successful bone marrow transplantation in a patient with Schimke immuno-osseous dysplasia
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DOI：
10.1067/mpd.2000.109147
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发表时间：
2000-12-01
影响因子：
5.1
通讯作者：
Castle, VP
中科院分区：
文献类型：
--
作者：
Petty, EM;Yanik, GA;Castle, VP
Schimke免疫性骨发育不良的早期死亡通常由肾功能衰竭和/或细胞介导的免疫缺陷引起。肾移植可以改善肾功能，但对免疫缺陷的有效治疗尚未报道。我们描述了一个患有Schimke免疫性骨发育不良的男孩在骨髓移植后2年骨髓功能明显改善。
Early death in Schimke immune-osseous dysplasia often results from renal Failure and/or cell-mediated immunodeficiency. Kidney transplants have improved renal function, but effective therapy for the immunodeficiency has not yet been reported. We describe markedly improved marrow function 2 years after bone marrow transplantation in a boy with Schimke immunoosseous dysplasia.