A novel three-component one-pot synthesis of 1H-imidazol-4-yl-pyridines

A novel three-component one-pot synthesis of 1H-imidazol-4-yl-pyridines
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DOI:
10.1021/ol0480269
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发表时间:
2005-01-06
期刊:
影响因子:
5.2
通讯作者:
Friedrich, C
Friedrich, C
中科院分区:
化学1区
文献类型:
--
作者:
Illgen, K;Nerdinger, S;Friedrich, C

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本发明描述了一种新颖的由醛、邻甲基吡啶胺和异氰化物生成1H-咪唑-4-基-吡啶的三组分一锅缩合反应。反应的范围和限制进行了研究。
A novel three-component, one-pot condensation yielding 1H-immidazol-4-yl-pyridines from aldehydes, o-picolylamines, and isocyanides is described. The scope and limitations of the reaction have been investigated.