Hodgkin's disease mortality in Europe.
Hodgkin's disease mortality in Europe.
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DOI：
10.1038/bjc.1991.388
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发表时间：
1991-10
影响因子：
8.8
通讯作者：
Boyle, P
中科院分区：
文献类型：
--
作者：
La Vecchia, C;Levi, F;Lucchini, F;Kaye, S B;Boyle, P
对16个西欧国家和7个东欧国家1950年代中期至1980年代后期霍奇金病死亡率的趋势进行了分析。从20世纪60年代后期开始，所有西方国家的死亡率都出现了大幅度的福尔斯下降，男性和女性的死亡率总体平均下降了50%，尽管北欧国家的福尔斯下降幅度更大（丹麦和瑞典接近70%），葡萄牙、西班牙和希腊的下降幅度更小（20%至30%）。霍奇金病死亡率的下降在年轻人（35岁以下）和中年人（35至64岁）以及15岁以下儿童中都很明显，在一些国家，老年人（65岁以上）也是如此。它们一直持续到最近的日历时期，没有证据表明它们会变平。霍奇金病死亡率的趋势模式在东欧有很大不同。在所审查的七个国家中，只有保加利亚和捷克斯洛伐克有所下降，但其他国家没有显示出一致的模式，也有一些增加。就绝对值而言，西欧霍奇金病死亡率的降低相当于每年避免3，000多例死亡。这就强调了提高目前确定的知识和资源在东欧霍奇金病治疗的可用性的重要性和紧迫性。
Trends in mortality from Hodgkin's disease between mid 1950s and the late 1980s have been analysed for 16 western European and seven eastern European countries. In all western countries there were substantial falls in mortality from the late 1960s onwards, for an overall mean decline of 50% in both sexes, although these falls were somewhat larger in Nordic countries (approaching 70% in Denmark and Sweden), and more limited (20 to 30%) in Portugal, Spain and Greece. The reductions in Hodgkin's disease mortality were evident both in younger (under 35) and middle age (35 to 64 years), as well as in children under 15 and, in several countries, in the elderly (above 65), too. They were persistent up to the most recent calendar periods, with no evidence of flattening off. The pattern of trends in Hodgkin's disease mortality was largely different in Eastern Europe. Among seven countries examined, some fall was observed only in Bulgaria and Czechoslovakia, but other countries showed no consistent pattern and there was some increase, too. In absolute terms, the reductions in Hodgkin's disease mortality in Western Europe correspond to the avoidance of over 3,000 deaths per year. This stresses the importance and urgency of improving the availability of currently defined knowledge and resources for treatment of Hodgkin's disease in Eastern Europe.