Preventing cardiovascular disease and diabetes - A call to action from the American Diabetes Association and the American Heart Association
Preventing cardiovascular disease and diabetes - A call to action from the American Diabetes Association and the American Heart Association
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DOI：
10.1161/circulationaha.106.176583
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发表时间：
2006-06-27
期刊：
影响因子：
37.8
通讯作者：
Rizza, Robert A.
中科院分区：
文献类型：
--
作者：
Eckel, Robert H.;Kahn, Richard;Rizza, Robert A.
远远超过了建造它们的人口。不过，有一个这样的工具（可在因特网上免费获得，网址为http：//www.糖尿病org/diabetesphd），其已经在许多广泛不同的临床试验中得到广泛验证，并且其几乎包含了所有已知的CVD风险因素。虽然它可用于预测发生CVD/糖尿病的风险或发生糖尿病/CVD后的治疗效果，但该工具和其他风险评估算法很少用于临床实践。相反，新出现的证据表明，简单地确定一个人的血糖水平，血压，低密度脂蛋白胆固醇水平和烟草使用，并注意肥胖的存在可能足以启动适当的干预措施，以预防或识别糖尿病和新出现的心血管疾病。22，24，50，51即使是临界异常，特别是如果它们是多个，也可能预示着未来的问题，应该加以解决。当然，关于每个风险因素的相对影响，风险因素的层次结构，其他风险因素的包含以及所有风险因素之间的关系，仍然存在一些有趣的科学问题;然而，至少，我们鼓励提供者认识到这些关键参数。
much beyond the population from which they were constructed. There is one such tool, however (available free on the Internet at http://www. diabetes. org/diabetesphd), that has been extensively validated across many widely differing clinical trials, and it incorporates virtually all known CVD risk factors. Although it can be used to predict the risk of developing CVD/diabetes or the effects of treatment after developing diabetes/CVD, this tool and other risk-assessment algorithms are rarely used in clinical practice. Conversely, emerging evidence suggests that simply ascertaining a person’s blood glucose level, blood pressure, LDL cholesterol level, and tobacco use and noting the presence of obesity may be sufficient to initiate the appropriate interventions to prevent or identify diabetes and emerging CVD. 22, 24, 50, 51 Even borderline abnormalities, especially if they are multiple, may well presage future problems and should be addressed. Certainly, a number of intriguing scientific questions remain regarding the relative impact of each risk factor, the hierarchy of risk factors, the inclusion of other risk factors, and the relationships among all of them; however, at the very least, we encourage providers to be cognizant of these key parameters.