Eusocial insect queens show costs of reproduction and transcriptomic signatures of reduced longevity
Eusocial insect queens show costs of reproduction and transcriptomic signatures of reduced longevity
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真社会性昆虫皇后表现出繁殖成本和寿命缩短的转录组特征
DOI：
10.1101/2022.03.20.485028
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Collins D
中科院分区：
文献类型：
--
作者：
Collins D
真社会性昆虫女王被认为是由于缺乏繁殖成本而衰老的标准进化理论的反例。使用大黄蜂（熊蜂terrestris），我们测试了这一假设的替代品，即繁殖成本存在于真社会性昆虫皇后，但潜伏的，通常发现在未经处理的皇后，导致在积极的生育力长寿的关系。我们通过移除蚁后的卵来实验性地增加蚁后的繁殖成本，这会导致蚁后增加产卵率。处理皇后有显着减少寿命相对于对照皇后的产卵率没有增加。此外，基于mRNA-seq，处理和对照蜂王在其总体表达谱和衰老相关基因的表达方面存在年龄相关基因表达差异。值得注意的是，这主要发生在相对年龄方面，而不是实足年龄。这些结果提供了第一个同时表型和转录组学的实验证据，在真社会性昆虫女王的繁殖成本，并建议如何支持衰老的遗传途径可能会在真社会性进化过程中被重塑。
Eusocial insect queens have been suggested to be counter-examples to the standard evolutionary theory of ageing through lacking costs of reproduction. Using the bumblebee (Bombus terrestris), we tested this hypothesis experimentally against the alternative that costs of reproduction exist in eusocial insect queens, but are latent, resulting in the positive fecundity-longevity relationship typically found in unmanipulated queens. We experimentally increased queens’ costs of reproduction by removing their eggs, which causes queens to increase their egg-laying rate. Treatment queens had significantly reduced longevity relative to control queens whose egg-laying rate was not increased. In addition, treatment and control queens differed in age-related gene expression based on mRNA-seq in both their overall expression profiles and the expression of ageing-related genes. Remarkably, this occurred principally with respect to relative age, not chronological age. These results provide the first simultaneously phenotypic and transcriptomic experimental evidence of costs of reproduction in queens of eusocial insects and suggest how the genetic pathways underpinning ageing might become remodelled during eusocial evolution.
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影响因子：
3.7
作者：
Kramer BH;Schrempf A;Scheuerlein A;Heinze J
通讯作者：
Heinze J
影响因子：
5.3
作者：
Rueppell, Olav;Aumer, Denise;Moritz, Robin F. A.
通讯作者：
Moritz, Robin F. A.
影响因子：
2
作者：
HAMILTON, WD
通讯作者：
HAMILTON, WD
影响因子：
3.1
作者：
R. Owen
通讯作者：
R. Owen
熊蜂工蜂在野外规模迁移到同种蜂巢
影响因子：
2.2
作者：
ZANETTE L
通讯作者：
ZANETTE L