Effect of Resveratrol on the Development of Porcine Embryos Produced In Vitro
Effect of Resveratrol on the Development of Porcine Embryos Produced In Vitro
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DOI：
10.1262/jrd.09-174k
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发表时间：
2010-06-01
影响因子：
1.8
通讯作者：
Machaty, Zoltan
中科院分区：
文献类型：
--
作者：
Lee, Kiho;Wang, Chunmin;Machaty, Zoltan
已经研究了白藜芦醇（一种具有多种药理活性的植物抗毒素）对单性生殖和/或体外受精产生的猪胚胎的影响。首先，在补充有不同量的白藜芦醇(0、0.05、0.1、0.5、1.0和25μM终浓度)的PZM-3培养基中产生并培养孤雌胚胎。与未处理的对照相比，在 0.5 μM 白藜芦醇存在的情况下，第 7 天达到囊胚阶段的孤雌胚胎的百分比显着更高（43.5 +/- 6.3% 对比 33.0 +/- 5.4%；P
The effects of resveratrol (a phytoalexin with a wide variety of pharmacological activities) on pig embryos produced by parthenogenesis and/or in vitro fertilization have been investigated. First, parthenogenetic embryos were generated and cultured in PZM-3 medium supplemented with various amounts of resveratrol (0, 0.05, 0.1, 0.5, 1.0 and 25 mu M final concentrations). In the presence of 0.5 mu M resveratrol a significantly higher percentage of parthenogenetic embryos reached the blastocyst stage by day 7 compared to non-treated control (43.5 +/- 6.3% vs. 33.0 +/- 5.4%; P