Neuronal activity related to elapsed time in prefrontal cortex
Neuronal activity related to elapsed time in prefrontal cortex
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DOI：
10.1152/jn.01011.2005
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发表时间：
2006-05-01
影响因子：
2.5
通讯作者：
Wise, SP
中科院分区：
文献类型：
--
作者：
Genovesio, A;Tsujimoto, S;Wise, SP
我们研究了在扫视任务中前额叶皮层的活动。在每一次试验中，视觉刺激的开始和它的抵消之间经历了三个延迟期之一，这引发了眼跳。刺激抵消后，许多神经元表现出阶段性的活动增加，这取决于前一个延迟期的持续时间。这种延迟依赖的活动变化只有微弱的反应时间，而是反映了一个更普遍的方面逝去的时间。
We studied prefrontal cortex activity during a saccade task. On each trial, one of three delay periods elapsed between the onset of a visual stimulus and its offset, which triggered a saccade. After stimulus offset, many neurons showed phasic increases in activity that depended on the duration of the preceding delay period. This delay-dependent activity varied only weakly with reaction time and instead appeared to reflect a more general aspect of elapsed time.