Tailored Duration of Contrast Material Injection in High-Pitch Computed Tomographic Aortography With a Double-Level Test Bolus Method
Tailored Duration of Contrast Material Injection in High-Pitch Computed Tomographic Aortography With a Double-Level Test Bolus Method
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DOI：
10.1097/rli.0000000000000340
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发表时间：
2017-05
影响因子：
6.7
通讯作者：
Tatsuya Nishii;Yoshiaki Watanabe;S. Shimoyama;A. Kono;K. Sofue;Shumpei Mori;Satoru Takahashi;K. Sugimura
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文献类型：
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作者：
Tatsuya Nishii;Yoshiaki Watanabe;S. Shimoyama;A. Kono;K. Sofue;Shumpei Mori;Satoru Takahashi;K. Sugimura
目的为了在高螺距CT血管成像中有效地使用造影剂（CM），适当的CM注射时间至关重要。我们使用了一种改进的双水平测试团注方法来确定适当的注射持续时间，目的是评价与固定持续时间相比，定制持续时间CM注射的图像质量。材料与方法机构审查委员会批准对80名连续受试者进行回顾性审查，这些受试者采用改良的双水平测试团注法接受了高螺距70-kVp CT血管造影。从时间/衰减曲线推导出主动脉根部和股动脉处的峰值增强之间的间隔。共有40名受试者接受了CT脑血管造影，并根据结果单独设定持续时间。其余受试者接受了固定持续时间的CT脑血管造影。评估主动脉几个部分的密度值。通过Welch检验评估用于每种方法的图像质量和CM量的差异。结果当个体定制时，注射持续时间缩短了近50%（中位数，15秒;范围，11-25秒）。平均CM量减少50%（分别为46.2-23.9 mL，P 0.05）。结论改进的双水平测试团注法在高螺距CT脑血管成像中可显著减少CM的量，且不影响图像质量。
Objectives To achieve the efficient usage of contrast material (CM) in high-pitch CT aortography, an appropriate duration of the CM injection is crucial. We used a modification of the double-level test bolus method for determination of proper injection duration with the aim of evaluating the image quality of tailored-duration CM injection compared with that of a fixed duration. Materials and Methods The institutional review board approved retrospective review of 80 consecutive subjects who had undergone high-pitch 70-kVp CT aortography with a modified double-level test bolus method. The interval between peak enhancement at the aortic root and femoral artery was derived from the time/attenuation curves. A total of 40 subjects underwent CT aortography with individually set duration time from the results. The remaining subjects underwent CT aortography with a fixed-duration time. The density values at several parts of the aorta were assessed. The differences in image quality and CM amount used for each method were assessed by Welch test. Results The injection duration was almost 50% shorter (median, 15 seconds; range, 11–25 seconds) when individually tailored. The mean CM amount was reduced by 50% (46.2–23.9 mL, P 0.05, respectively). Conclusions The modified double-level test bolus method in high-pitch CT aortography can significantly reduce the amount of CM without adversely affecting image quality.