Clinical features of 46 eyes with calcified hydrogel intraocular lenses
Clinical features of 46 eyes with calcified hydrogel intraocular lenses
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DOI：
10.1016/s0886-3350(01)01038-0
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发表时间：
2001-10
影响因子：
2.8
通讯作者：
A. K. Yu;K. Y. W. Kwan;David Ho Yin Chan;Daniel Y. T. Fong
中科院分区：
文献类型：
--
作者：
A. K. Yu;K. Y. W. Kwan;David Ho Yin Chan;Daniel Y. T. Fong
PurposeTo clarify the clinical features of delayed calcification of hydrogel intraocular lenses (IOLs) based on observation of a large case series.SettingOphthalmology department of 2 university teaching hospitals, Hong Kong, China.MethodsThe first 44 patients with a known diagnosis of calcified IOL were recruited. Medical and ophthalmic histories were obtained. Surgical details, surgical complications, and visual acuity before and after IOL implantation were also retrieved. Patients then had a visual acuity test, a slitlamp examination of the features of the IOL calcification, and a fundus examination for clarity of view.ResultsForty-six eyes of 44 patients had IOL calcification. All had a Hydroview IOL. The onset was from 4 to 26 months after surgery. Ninety-three percent of eyes had generalized IOL calcification, and 96% had forceps marks on the IOL. Mean visual acuity deteriorated from 0.4 at 3 months to 0.13 at 19 months. Visual loss was more severe in patients with diabetes mellitus or ischemic heart disease and in those in which the IOL calcified earlier after implantation.ConclusionAll cases of IOL calcification were delayed in onset. The presence of forceps marks may provide a clue to the pathogenesis. Bilateral but asymmetric involvement in 2 patients suggests that the IOL was involved in the pathogenesis. Affected patients lost an average of 2.8 Snellen lines of visual acuity. Some eyes progressed more rapidly; however, the modulating factors remain unknown.
