Hypogammaglobulinemia in children undergoing continuous ambulatory peritoneal dialysis.
Hypogammaglobulinemia in children undergoing continuous ambulatory peritoneal dialysis.
复制标题
接受连续不卧床腹膜透析的儿童发生低丙种球蛋白血症。
DOI：
10.1007/bf00852907
复制
发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Lederman,HM
中科院分区：
文献类型：
--
作者：
Fivush,BA;Case,B;May,MW;Lederman,HM
Humoral immunity was evaluated in seven children undergoing continuous ambulatory peritoneal dialysis (CAPD). Five children (71%) had serum immunoglobulin levels which were more than 2 SD below the mean for age. One mechanism contributing to hypogammaglobulinemia was loss via the peritoneal membrane. Daily losses of IgG into peritoneal dialysis effluents represented 7%–29% of normal daily IgG synthesis, and losses increased with duration of CAPD therapy. Despite the observed hypogammaglobulinemia, all children had protective antibody responses to immunization.
