Breast cancer measurements with magnetic resonance imaging, ultrasonography, and mammography
Breast cancer measurements with magnetic resonance imaging, ultrasonography, and mammography
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DOI：
10.1007/bf01806626
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发表时间：
1996-01-01
影响因子：
3.8
通讯作者：
Tobon, H
中科院分区：
文献类型：
--
作者：
Davis, PL;Staiger, MJ;Tobon, H
背景：随着乳腺癌治疗的进展，准确测量乳腺癌的大小变得越来越重要。本研究报告了磁共振成像（MRI）、超声和乳房x线摄影测量最大乳腺癌直径的准确性与病理测量的比较。材料与方法：对13例乳腺癌患者进行MRI、超声和乳房x光检查。年龄31 ~ 73岁，平均56岁。6例癌症发生在绝经前妇女身上。MRI通过静脉注射钆造影剂和三维快速破坏梯度回波序列进行，脂肪抑制。用每种成像技术测量最大肿瘤直径，并与病理测量的最大肿瘤直径进行比较。结果：病理检查肿瘤最大直径0.6 ~ 6cm（平均2.2）。MRI测量结果的相关系数最高（r = 0.98），标准误差最小（0.34）。超声测量的相关系数为r = 0.45，标准误差为0.78。乳房x线摄影测量的相关系数r = 0.46，标准误差1.04。结论：在本组妇女中，MRI比超声检查和乳房x光检查更准确地测量出肿瘤的最大直径。这在一些较大的癌症和化疗后的癌症中尤为明显。
Background: Accurate measurement of the size of breast cancers becomes more important as breast cancer therapy advances. This study reports the accuracy of magnetic resonance imaging (MRI), ultrasonography and mammography for measuring the largest breast cancer diameter in comparison to the pathology measurement.Materials and methods: Fourteen breast cancers were examined in 13 women with MRI, ultrasonography and mammography. The age range was 31-73 (mean 56). Six of the cancers were in premenopausal women. The MRI was performed with the intravenous injection of gadolinium based contrast agent and a three dimensional fast spoiled gradient echo sequence with fat suppression. The largest cancer diameter was measured with each imaging technique and compared to the largest cancer diameter measured at pathology.Results: At pathological examination cancers ranged from 0.6 to 6 cm (mean 2.2) in largest diameter. MRI measurements had the highest correlation coefficient (r = 0.98) and the smallest standard error (0.34). Ultrasonography measurements had a correlation coeffient of r = 0.45 and a standard error of 0.78. Mammography measurements had a correlation coefficient of r = 0.46 and a standard error of 1.04.Conclusions: MRI was more accurate than ultrasonography and mammography in measuring the largest cancer diameters in this group of women. This was particularly evident for several larger cancers, and a post-chemotherapy cancer.