The Value of Being Wrong: Intermittent Feedback Delivery Alters the Striatal Response to Negative Feedback.
The Value of Being Wrong: Intermittent Feedback Delivery Alters the Striatal Response to Negative Feedback.
复制标题
错误的价值：间歇性的反馈传递改变了纹状体对负面反馈的反应。
DOI：
10.1162/jocn_a_00892
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发表时间：
2016
影响因子：
3.2
通讯作者：
Tricomi,Elizabeth
中科院分区：
文献类型：
--
作者：
Lempert,KarolinaM;Tricomi,Elizabeth
积极的反馈既能带来奖励，也能提供信息，而消极的反馈可以被理解为惩罚（因为它表明表现不佳）或信息（因为它可能导致目标的实现）。在这个神经成像实验中，我们通过混合有反馈和没有反馈的实验来突出负反馈的信息价值。当预期表现反馈时，正反馈触发纹状体活动的增加，而负反馈则引起纹状体活动的减少。我们预测，相反，当反馈接收不可预测时，纹状体对负反馈的反应会增加。参与者在fMRI扫描期间执行配对联想学习任务。在一种情况下（“屏蔽反馈”），反馈的接收是可以预测的——参与者知道他们的回答是否会收到反馈。在另一种情况下（“混合反馈”），反馈的接收是不可预测的——在随机的50%的试验中，参与者收到反馈，否则他们没有收到反馈。混合反馈条件下的负反馈比阻断反馈条件下的负反馈引起更多的纹状体活动。相比之下，反馈遗漏在预期反馈传递时比在无法预测反馈传递时诱发更多纹状体活动。这种模式出现在混合反馈条件下，在负反馈条件下尾状体活动增加，在无反馈条件下腹侧纹状体活动减少。这些结果表明，通过强调负反馈的信息价值，不可预测的反馈环境改变了纹状体对负反馈和遗漏反馈的反应。
Whereas positive feedback is both rewarding and informative, negative feedback can be construed as either punishing (because it is indicative of poor performance) or informative (because it may lead to goal attainment). In this neuroimaging experiment, we highlighted the informational value of negative feedback by intermixing trials with and without feedback. When performance feedback is expected, positive feedback triggers an increase in striatal activity, whereas negative feedback elicits a decrease in striatal activity. We predicted that, in contrast, when feedback receipt is unpredictable, the striatal response to negative feedback would increase. Participants performed a paired-associate learning task during fMRI scanning. In one condition (“blocked feedback”), the receipt of feedback was predictable—participants knew whether or not they would receive feedback for their responses. In another condition (“mixed feedback”), the receipt of feedback was unpredictable—on a random 50% of trials, participants received feedback, and they otherwise received no feedback. Negative feedback in the mixed feedback condition elicited more striatal activity than negative feedback in the blocked feedback condition. In contrast, feedback omission evoked more striatal activity when feedback delivery was expected, compared to when it was unpredictable. This pattern emerged from an increase in caudate activity in response to negative feedback in the mixed feedback condition and a decrease in ventral striatal activity in response to no feedback in this condition. These results suggest that, by emphasizing the informational value of negative feedback, an unpredictable feedback context alters the striatal response to negative feedback and to the omission of feedback.