Electrochemical impedance spectroscopy study of the passive oxide film on titanium for implant application
Electrochemical impedance spectroscopy study of the passive oxide film on titanium for implant application
复制标题
DOI：
10.1016/0013-4686(95)00465-3
复制
发表时间：
1996-05-01
影响因子：
6.6
通讯作者：
Leygraf, C
中科院分区：
文献类型：
--
作者：
Pan, J;Thierry, D;Leygraf, C
钛表面氧化膜及其在生物环境中的长期稳定性对钛植入物的生物相容性起着决定性作用。在这项研究中，钛和它的自然生长在磷酸盐缓冲溶液中，有和没有H2O2添加形成的钝化氧化膜已通过电化学阻抗谱（EIS）测量超过几个星期的时间进行了研究。在不存在H2O2的情况下，阻抗响应表明在钛上形成稳定的薄氧化膜。然而，将H2O2引入到溶液中导致EIS光谱的显著变化，其随曝光时间而变化。结果的解释是基于一个两层模型的氧化膜，由一个薄的屏障型内层和多孔外层。溶液中的H2O2添加导致钛的耐腐蚀性显著降低，并且还导致多孔外层增厚。这些观察结果可以解释体内非预期的钛氧化物生长和离子掺入钛植入物氧化物表面。
The surface oxide film on titanium and its long-term stability in biological environments play a decisive role for the biocompatibility of titanium implants. In this study, the passive oxide film formed on titanium and its natural growth in a phosphate buffered solution with and without an H2O2 addition have been investigated by electrochemical impedance spectroscopy (EIS) measurements over a period of several weeks. In the absence of H2O2, the impedance response indicated a stable thin oxide film on titanium. However, the introduction of H2O2 into the solution resulted in significant changes in the EIS-spectra, which varied with exposure time. The interpretation of results is based upon a two-layer model of the oxide film, consisting of a thin barrier-type inner layer and a porous outer layer. The H2O2 addition in the solution led to a significant decrease in corrosion resistance of titanium and also to a thickening of the porous outer layer. The observations may provide an explanation of the unexpected in vivo titanium oxide growth and ion incorporation into titanium implant oxide surfaces.