ROTATIONAL DEFORMATION OF THE CANINE LEFT-VENTRICLE MEASURED BY MAGNETIC-RESONANCE TAGGING - EFFECTS OF CATECHOLAMINES, ISCHEMIA, AND PACING
ROTATIONAL DEFORMATION OF THE CANINE LEFT-VENTRICLE MEASURED BY MAGNETIC-RESONANCE TAGGING - EFFECTS OF CATECHOLAMINES, ISCHEMIA, AND PACING
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DOI：
10.1093/cvr/28.5.629
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发表时间：
1994-05-01
影响因子：
10.8
通讯作者：
SHAPIRO, EP
中科院分区：
文献类型：
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作者：
BUCHALTER, MB;RADEMAKERS, FE;SHAPIRO, EP
目的：目的是通过磁共振标记（一种标记心肌的非侵入性方法）在犬模型中研究左心室心尖相对于基部旋转的产生。方法：对 18 只狗进行基线和以下期间的成像：(1) 用多巴酚丁胺进行正性肌力刺激； (2) 心房起搏变时刺激； (3)前壁缺血； (4)后壁缺血； (5) 改变左心室激动部位；每次干预有六只狗接受。量化顶点的旋转（扭转）。心外膜和心内膜以及前壁和后壁分别考虑。结果：心外膜平均扭转[前3.1（SEM 1.2）度，后9.9（1.0）度]小于心内膜[前8.1（2.6）度，后14.9（2.0）度，p
Objective: The aim was to investigate the generation of rotation of the left ventricular apex with respect to the base by magnetic resonance tagging, a non-invasive method of labelling the myocardium, in a canine model. Methods: 18 dogs were imaged at baseline and during: (1) inotropic stimulation with dobutamine; (2) chronotropic stimulation with atrial pacing; (3) anterior wall ischaemia; (4) posterior wall ischaemia; and (5) varying left ventricular activation site; six dogs underwent each intervention. Apical rotation of the apex (torsion) was quantified. The epicardium and the endocardium were considered separately, as were the anterior and posterior walls. Results: Mean torsion of the epicardium [anterior 3.1(SEM 1.2)degrees, posterior 9.9(1.0)degrees] was less than that of the endocardium [anterior 8.1(2.6)degrees, posterior 14.9(2.0)degrees, p