Malnutrition associated with unfavorable outcome and death among South African MDR-TB and HIV co-infected children
Malnutrition associated with unfavorable outcome and death among South African MDR-TB and HIV co-infected children
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DOI：
10.5588/ijtld.14.0231
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发表时间：
2014-09-01
影响因子：
4
通讯作者：
O'Donnell, M. R.
中科院分区：
文献类型：
--
作者：
Hicks, R. M.;Padayatchi, N.;O'Donnell, M. R.
背景：儿童耐多药结核病 (MDR-TB) 诊断困难、治疗复杂且死亡率高。在南非，人类免疫缺陷病毒（HIV）合并感染加剧了这些挑战；然而，关于合并感染儿童治疗结果的证据有限。 目的：使用传统和新的儿科定义，描述治疗结果并确定老年儿童不良结果和死亡率的危险因素
SETTING: Pediatric multidrug-resistant tuberculosis (MDR-TB) is complicated by difficult diagnosis, complex treatment, and high mortality. In South Africa, these challenges are amplified by human immunodeficiency virus (HIV) co-infection; however, evidence on treatment outcomes among co-infected children is limited.OBJECTIVE: Using conventional and new pediatric definitions, to describe treatment outcomes and identify risk factors for unfavorable outcome and mortality in children aged