Missing the forest for the trees? Deficient memory for linguistic gist in obsessive-compulsive disorder
Missing the forest for the trees? Deficient memory for linguistic gist in obsessive-compulsive disorder
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DOI：
10.1017/s0033291701004354
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发表时间：
2001-08-01
影响因子：
6.9
通讯作者：
Savage, CR
中科院分区：
文献类型：
--
作者：
Cabrera, AR;McNally, RJ;Savage, CR
背景资料。强迫症(OCD)患者在词汇学习任务中表现出回忆缺陷，这是由于他们未能发现单词之间的语义联系。本实验采用Bransford&Franks(1971)提出的方法，检验编码问题是否会影响他们从复杂语言材料中提取主旨。与我们的假设一致，强迫症患者从相关句子中提取的要点比健康参与者少。两组在对单个句子的再认记忆、以记忆敏感度(d‘)和反应偏差(Beta)为信号检测指标的确认先前遇到的句子为“旧”的标准上没有差异，在再认记忆置信度上也没有差异。这些数据进一步证明，与健康对照组参与者相比，强迫症患者对组织策略的依赖程度更低。这些数据与神经心理学研究暗示的强迫症前额叶执行问题是一致的。
Background. Patients with obsessive-compulsive disorder (OCD) exhibit recall deficits on word learning tasks, mediated by their failure to detect semantic connections among the words.Methods. In the present experiment, using methods devised by Bransford & Franks (1971), we tested whether this encoding problem impairs their extraction of gist from complex linguistic material.Results. Consistent with our hypothesis, OCD patients extracted less gist from related sentences than did healthy participants. The groups did not differ in recognition memory for individual sentences or in criterion for affirming previously encountered sentences as 'old', as evinced by signal detection indices of memory sensitivity (d ') and response bias (beta), or in recognition memory confidence.Conclusions. These data provide further evidence that OCD patients exhibit less reliance on organizational strategies than do healthy control participants. These data are consistent with neuropsychological research suggestive of prefrontal executive problems in OCD.