Sex differences in the relationship between activity and weight loss in the rat
Sex differences in the relationship between activity and weight loss in the rat
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DOI：
10.1037/0735-7044.113.5.1080
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发表时间：
1999-10-01
影响因子：
1.9
通讯作者：
Single, JP
中科院分区：
文献类型：
--
作者：
Boakes, RA;Mills, KJ;Single, JP
在同窝雄性和雌性大鼠中，使用转轮结合限制喂养以相同的速率产生体重减轻（实验1）。因此，尽管体重较轻，跑步较多，但女性并不更容易受到这种程序的影响。当影响体重减轻的因素不同，没有性别差异，发现在适应一个新的喂养时间表或在单一与组住房的影响（实验2）。明显的关键差异是，体重减轻增加男性，但不是女性（实验3）运行。在所有大鼠中，当食物获取不再受到限制时，体重迅速恢复（实验1），这表明“基于活动的厌食症”是在转轮中大鼠体重减轻的误称。
Access to a running wheel combined with restricted feeding produced body weight loss at an equivalent rate in male and female litter-mate rats (Experiment 1). Thus, despite weighing less and running more, females were not more vulnerable to this procedure. When factors influencing weight loss were varied, no sex difference was found in adaptation to a new feeding schedule or in the effect of single versus group housing (Experiment 2). The apparent critical difference was that body weight loss increased running in males but not in females (Experiment 3). In all rats, rapid recovery of body weight occurred when food access was no longer restricted (Experiment 1), suggesting that "activity-based anorexia" is a misnomer for weight loss by rats in a running wheel.