Protein Staining Agents from Cationic and Neutral Luminescent Iridium(III) Complexes
Protein Staining Agents from Cationic and Neutral Luminescent Iridium(III) Complexes
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阳离子和中性发光铱 (III) 络合物的蛋白质染色剂
DOI：
10.1002/chem.201603630
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Xu Nan
中科院分区：
文献类型：
--
作者：
Zhou Yuyang;Jia Junli;Wang Xiaomei;Guo Weiqiang;Wu Zhengying;Xu Nan
制备了7种发光铱（III）配合物，研究了其化学结构与蛋白质染色性能之间的关系。首次揭示了主配体、辅助配体的π共轭效应和有机金属配合物的电荷效应对蛋白质染色的影响。最重要的是，这项研究首次提供了电中性有机金属配合物在蛋白质染色中潜在应用的实验证据，这可能为未来开发新型蛋白质染色剂开辟一条途径。
Seven luminescent iridium(III) complexes were prepared to investigate the relationships between chemical structures and properties of protein staining. For the first time, the effect of the main ligand, the π conjugation effect of the ancillary ligand, and the charge effect of organometallic complexes on protein staining has been revealed. Most importantly, this study gives the first experimental evidence of the potential applications of charge‐neutral organometallic complexes in protein staining, which could open an avenue of exploiting novel protein staining agents in the future.