Risk of Recurrence of Colon Polyps
Risk of Recurrence of Colon Polyps
复制标题
结肠息肉复发的风险
作者：
L. G. Henry;R. Condon;W. Schulte;C. Aprahamian;J. Decosse
在伍德退伍军人管理中心，268名接受息肉切除术的患者接受了长达20年的随访，每半年进行一次直肠乙状结肠镜和钡灌肠检查。对于良性息肉病的本综述，排除了共存癌、慢性炎性疾病和失访的患者;研究组包括154例平均随访7年的患者。30%的患者出现复发性息肉。在第一年复发的风险是16倍，在类似的年龄和性别的人口预期，但此后稳步下降。48个月后，息肉复发的风险略高于正常人群的预期发病率。无论是患者的年龄，症状，还是最初息肉的部位或大小，都没有任何复发的预后价值。绒毛状腺瘤或超过3个息肉的患者复发风险显著增加，可能无限期持续。结肠癌的总体发病率可能增加，但随后的癌症的位置与先前切除的息肉的位置无关。
At Wood Veterans Administration Center, 268 patients who had a polypectomy have been followed up to 20 years with semiannual proctosigmoidoscopic and barium enema examinations. For the present review of benign polyp disease, patients having coexisting carcinoma, chronic inflammatory disease, and those lost to followup have been excluded; 154 patients followed for a mean of 7 years comprise the study group. Thirty per cent of patients developed recurrent polyps. The risk of recurrence during the first year was 16 times that expected in a population of similar age and sex, but thereafter diminished steadily. After 48 months risk of polyp recurrence was little higher than the incidence expected in a normal population. Neither patient age, presenting symptoms nor the site or size of the initial polyp(s) were of any prognostic value regarding recurrence. Patients presenting with a villous adenoma or with more than 3 polyps had a significantly increased risk of recurrence may persist indefinitely. The overall incidence of colonic carcinoma may have been increased, but the location of subsequent cancer was not related to the site of a previously excised polyp.